Energy Evaluation of MW effects on ACh receptor channels with parallel computing

Apollonio F, D'Inzeo G, Tarricone L.

Electromag. Biol. Med. 19:69-79, 2000

We present an evaluation of the effects of microwave fields on the acetylcholine (ACh) receptor channel, based on energy issues. The channel is considered a stochastic automaton, flipping randomly from one state to another, and the incident field modifies transitions among the states.

The observation of some appropriate biochemical parameters demonstrates that microwave fields cause conformational changes in the receptor site.

An energetic mapping of ACh conformational changes is also achieved, clearing the ground for future development of this research in the field of molecular simulations.